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Syorell R&D

Next-generation sun protection, born from boron.

We are bringing boron, one of Türkiye’s richest natural resources, into the science of sun protection. TÜBİTAK-funded research, carried out with a university and protected by patent applications.

Our technology

Power from beneath the earth, now beneath the sun.

Our R&D platform is built on a next-generation boron technology: the science that turns boron, one of Türkiye’s richest resources, into high-performance cosmetic actives.

We have synthesised 18 distinct boron bioactives so far. The library is among the first to bring boron chemistry into UV photoprotection and is protected by nine patent applications. In screening tests our lead active reached up to SPF 89 on its own.

18boron bioactives synthesised
89highest SPF measured with a single active
9patent applications
5lead actives ready to scale
Protect and support

Actives that do two jobs at once.

Our boron actives raise photoprotection and neutralise the oxidative stress UV creates in the skin, helping protect the cellular machinery the skin needs to renew itself. They were non-cytotoxic in cell studies and showed protective effects against both UVA- and UVB-induced photoageing.

TÜBİTAK-funded project

Boron in sun protection.

TÜBİTAK 1505 University and Industry Programme Project No. 5240069 Atatürk University Faculty of Medicine, Pharmacology 18 months · December 2024 to May 2026

By combining boron, Türkiye’s strategic natural resource, with bioactive molecules, we have developed a first-of-its-kind cosmetic active that brings boron into sun protection and helps the skin repair UV damage. The project was carried out under the TÜBİTAK 1505 University and Industry Programme with the Department of Pharmacology at Atatürk University’s Faculty of Medicine.

Why now?

Climate change is lengthening our exposure to UV.

Rising UVMore exposure, more harmAs the ozone layer thins, more UV reaches the ground and the need for sun protection is growing fast.
Multifunctional demandSPF is no longer enoughConsumers now expect antioxidant, anti-ageing and anti-spot benefits in the same product.
Ecosystem pressureKinder chemistryRoughly 14 million litres of sunscreen reach the Mediterranean each year; demand for mineral and natural filters is climbing fast.
Import dependenceA home-grown activeLocal formulators pay 150 to 1,000 euros per kilo for imported active ingredients. A domestic boron active reduces that dependence.
+167%rise in mineral UV filter demand over 5 years
$16Bprojected global sun care market by 2031
~50%raw material cost advantage over imports
The science

Boron esters: a new generation of SPF actives.

Boric acid readily binds the cis diol groups of certain bioactive molecules. Using this, boron was esterified with proven skin actives and stabilised with sodium, calcium and zinc counter-ions, giving a family of boron ester actives that both protect and nourish the skin.

Lead candidatePyridoxine · vitamin B6Binds boron through its phenolic group, with a crystal structure confirmed by single-crystal X-ray diffraction. It sits at the centre of high-protection systems that need little or no chemical UV filter.
Antioxidant and SPF synergyVitamin CThe ascorbate anion reacts with boric acid at its cis diol position, giving mono and di ester forms that pair sun protection with antioxidant defence.
Barrier and hydrationHyaluronic acidA high molecular weight hyaluronate is built into the ester structure to add skin barrier support and moisture retention.
Preliminary results

Up to 3 times the SPF.

With zinc oxide held constant, the boron esters raised SPF up to 3 times over baseline, reaching about SPF 89 with a single active. No cytotoxic effect was seen on skin fibroblasts, and antioxidant and anti-photoageing activity was measured.

A first for its field

No prior patent or product for boron in UV protection.

Compared with leading multifunctional sunscreens, the project output stands out for skin barrier protection and soothing effect while using fewer chemical filters, thanks to its boron ascorbate and boron pyridoxine chemistry. No patent or commercial product was found for the use of boron compounds with bioactive molecules for UV protection: a genuine first in application, and a step that strengthens Türkiye’s place in the boron value chain.

Intellectual property

Nine patent applications.

Filed with the Turkish Patent and Trademark Office on 17 July 2025, the applications cover boron esters of pyridoxine (vitamin B6), hyaluronic acid and vitamin C as calcium, zinc and sodium salts. Each is claimed for SPF enhancement and the prevention of UVA- and UVB-induced skin damage.

#ApplicationNo.
1Boron pyridoxine mono and di ester calcium salts2025/009860
2Boron pyridoxine mono and di ester zinc salts2025/009859
3Boron pyridoxine mono and di ester sodium salts2025/009861
4Boron hyaluronic acid mono and di ester calcium salts2025/009856
5Boron hyaluronic acid mono and di ester zinc salts2025/009858
6Boron hyaluronic acid mono and di ester sodium salts2025/009857
7Boron ascorbic acid (vitamin C) mono and di ester calcium salts2025/009825
8Boron ascorbic acid (vitamin C) mono and di ester zinc salts2025/009824
9Boron ascorbic acid (vitamin C) mono and di ester sodium salts2025/009827
As raw materials

Five lead actives, ready for formulas.

From the 18 synthesised boron esters, five lead actives are ready to scale. Each reaches SPF 50+, shows strong antioxidant and anti-photoageing performance, is non-cytotoxic in cell studies and is designed to lower the mineral filter load.

01Barrier SupportMono Pyridoxine Ca · SPF 50+
02BalanceMono Pyridoxine Zn · SPF 50+
03Renewal SupportDi Pyridoxine Na · SPF 50+
04Antioxidant DefenceDi Ascorbate Na · SPF 50+
05Firming and Anti-AgeingDi Ascorbate Ca · SPF 50+

This page shares the science and the shape of the project. Component ratios, doses, synthesis routes and raw data are confidential and shared only under a non-disclosure agreement. The boron actives are at the R&D stage and are not contained in any Syorell product currently on sale.

Project team

Among Türkiye’s leading names in the field.

Prof. Dr. Zekai HalıcıProject lead · Pharmacology, Atatürk University. TÜBİTAK Young Scientist and Eczacıbaşı awards; boron work with BOREN and TÜSEB.
Prof. Dr. Elif ÇadırcıResearcher · Pharmacology. Extensive publications and projects on boron.
Prof. Dr. Dursun Ali KöseResearcher · Chemistry, Hitit University. Responsible for synthesis and characterisation.
Assoc. Prof. Zerrin KutluResearcher · Pharmacology. In vitro analysis lead.

Infrastructure: Atatürk University’s DAYTAM centre and Syorell’s own pilot production line. Syorell is ISO 9001 and Leaping Bunny certified, and was the first brand in Türkiye to use the MicNo® zinc oxide UV filter.

Management

The team behind Syorell.

M. Kerim Çekiç

M. Kerim Çekiç

Founder

  • Entrepreneur for 30 years across chemistry, cosmetics and biotechnology
  • Founder of Syorell; sets the company’s strategy and direction
  • First in Türkiye to use MicNo, the EU innovation award-winning mineral UV filter, in a sunscreen
  • Introduced Alpha Glucosyl Rutin into formulations in Türkiye
Prof. Dr. Zekai Halıcı

Prof. Dr. Zekai Halıcı

Head of Innovation and R&D

  • Leading Syorell’s innovation and R&D for 10 years
  • Lead of the TÜBİTAK-funded boron research project
  • Professor of Medical Pharmacology, Atatürk University, since 2014
  • Post-doctoral research, University of Florida College of Medicine
  • Director of the University Research and Application Centre; peer-reviewed work in pharmacology and boron compounds
Tuba Yazıcı Akbaş

Tuba Yazıcı Akbaş

Formulation and R&D

  • Nearly 7 years in R&D, laboratory and manufacturing
  • Product development, formulation, quality control analysis and commercial-scale production
  • Develops and optimises formulas, runs pilot trials and transfers them to production
  • On the TÜBİTAK boron project: formulation, pilot production, stability testing and optimisation
Çiğdem Bayrak

Çiğdem Bayrak

Regulatory, Quality and Project Management

  • Project manager of the TÜBİTAK-funded boron cosmetics R&D project, from research to implementation
  • Cosmetic safety assessment, regulatory compliance and Ministry of Health product registration
  • Manages product processes, from raw material sourcing to final delivery and export
  • Team management, laboratory research and cosmetic product development

The science is proven. The opportunity is open.

Our lab-validated, patent-pending boron actives are ready for formula adaptation and pilot production. Write to us about raw material supply, licensing and co-development.